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The exact mechanism of the phenomenon, termed endotoxin tolerance, is not known". Also, some experiments have shown which the endotoxin of your Legionnaires' bacillus has another spectrum of toxicity than the greater widespread gram-adverse organisms. Particularly the Legionnaires' endotoxin wasn't quite pyrogenic (by the rabbit examination), but was really active during the LAL - 1,000 fold difference between The 2 exams. In this case, the rabbit check is insufficient for analyzing the potency on the toxins present.
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